Changes in the organization of the genome during the mammalian cell cycle
1 Institut Curie, CNRS UMR3215, INSERM U934 26 rue d’Ulm, Paris, F-75248, France
2 Institut Curie, INSERM U900, Bioinformatics and Computational Systems Biology of Cancer, 26 rue d’Ulm, Paris, F-75248, France
Genome Biology 2013, 14:142 doi:10.1186/gb4147Published: 24 December 2013
By using chromosome conformation capture technology, a recent study has revealed two alternative three-dimensional folding states of the human genome during the cell cycle.