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Changes in the organization of the genome during the mammalian cell cycle

Luca Giorgetti1*, Nicolas Servant2 and Edith Heard1

Author Affiliations

1 Institut Curie, CNRS UMR3215, INSERM U934 26 rue d’Ulm, Paris, F-75248, France

2 Institut Curie, INSERM U900, Bioinformatics and Computational Systems Biology of Cancer, 26 rue d’Ulm, Paris, F-75248, France

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Genome Biology 2013, 14:142  doi:10.1186/gb4147

Published: 24 December 2013


By using chromosome conformation capture technology, a recent study has revealed two alternative three-dimensional folding states of the human genome during the cell cycle.