Biology for the post-genomic era
Fully Open Access. Genome Biology covers all areas of biology and biomedicine studied from a genomic and post-genomic perspective. Content includes research, new methods and software tools, and reviews, opinions and commentaries. Areas covered include, but are not limited to: sequence analysis; bioinformatics; insights into molecular, cellular and organismal biology; functional genomics; epigenomics; population genomics; proteomics; comparative biology and evolution; systems and network biology; genomics of disease; and clinical genomics. All content is open access immediately on publication.
- Louisa Flintoft PhD, Genome Biology
A method for predicting a sequence’s localization in the A or B compartment of the nucleus based on chromatin data
Robin Allaby discusses the origins of barley, and what this means for our understanding of the evolution of domesticated crops
A comparison of in-nucleus and in-solution ligation protocols for Hi-C finds that the former gives much more consistent results
Susan Gasser and colleagues discuss how the nuclear lamina interacts with chromatin and the implications this has for nuclear organization
A new study increases our understanding of the evolutionary genetic process associated with the transition from wild to domesticated barley
Jason Lieb discusses two recent publications which apply the ATAC-seq protocol to single cells
Chang Liu and Detlef Weigel review the current knowledge about three dimensional chromatin interactions in plants
Philip Avner and colleagues review new developments in understanding how the Xist long noncoding RNA functions in mammalian X chromosome inactivation.
This method is able to predict topologically associated domain boundaries and chromatin interaction hubs from histone modification ChIP-seq data
Comparison of CTCF and BORIS binding sites identifies two classes of binding event, with one or two binding sites
In this Review, Bouwman and De Laat discuss recent insights into the trans-acting factors that enable the genome to adopt different functionally relevant conformations.
Latest articles from Genome Medicine
Genome Medicine 2015, 7:94
Genome Medicine 2015, 7:93
Genome Medicine 2015, 7:92
Genome Medicine 2015, 7:91
From the blog
- 23 July 2015
- Haere mai to the kiwi genome