Additional file 9.

The MONGOOSE toolbox. The MONGOOSE (MetabOlic Network Growth OptimizatiOn Solved Exactly) toolbox [33] is a software suite we have developed, which gives certifiably correct results quickly and efficiently and is able to handle the largest metabolic model currently reconstructed. Its main features are the use of exact rational arithmetic, which avoids the risk of erroneous results due to rounding errors, as well as its ability to compress the metabolic network in order to speed up subsequent computations. This file describes in detail the algorithms underlying MONGOOSE [33].

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Chindelevitch et al. Genome Biology 2012 13:r6   doi:10.1186/gb-2012-13-1-r6