DNA-protein interactions in high definition
1 Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
2 Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA
3 Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Genome Biology 2012, 13:139 doi:10.1186/gb-2012-13-1-139Published: 27 January 2012
An elegant, genome-wide approach to define the precise DNA sequences bound by transcription factors has been developed by Rhee and Pugh.