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Sequencing the genome of the Burmese python (Python molurus bivittatus) as a model for studying extreme adaptations in snakes

Todd A Castoe1, AP Jason de Koning1, Kathryn T Hall1, Ken D Yokoyama1, Wanjun Gu2, Eric N Smith3, Cédric Feschotte3, Peter Uetz4, David A Ray5, Jason Dobry6, Robert Bogden6, Stephen P Mackessy7, Anne M Bronikowski8, Wesley C Warren9, Stephen M Secor10 and David D Pollock1*

Author Affiliations

1 Department of Biochemistry & Molecular Genetics, University of Colorado School of Medicine, 12801 17th Ave, Aurora, CO 80045, USA

2 Key Laboratory of Child Development and Learning Science, Southeast University, Si Pai Lou 2, Ministry of Education, Nanjing, 210096, China

3 Department of Biology, University of Texas, 501 S. Nedderman Dr., Arlington, TX 76019, USA

4 Center for Bioinformatics & Computational Biology, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA

5 Department of Biochemistry and Molecular Biology, Mississippi State University, 101 College Road, Mississippi State, MS 39762, USA

6 Amplicon Express, 2345 NE Hopkins Ct., Pullman, WA 99163, USA

7 School of Biological Sciences, 501 20th Street, University of Northern Colorado, Greeley, CO 80631, USA

8 Department of Ecology, Evolution, and Organismal Biology, Iowa State University, 253 Bessey Hall, Ames, IA 50011, USA

9 Genome Sequencing Center, Washington University School of Medicine, 4444 Forest Park Ave, St Louis, MO 63108, USA

10 Department of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35487, USA

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Genome Biology 2011, 12:406  doi:10.1186/gb-2011-12-7-406

Published: 28 July 2011


The Consortium for Snake Genomics is in the process of sequencing the genome and creating transcriptomic resources for the Burmese python. Here, we describe how this will be done, what analyses this work will include, and provide a timeline.