Simplified network from that presented in de Figueiredo et al. considering the question of conversion of fatty acids to sugars. AcCoA, acetyl-CoA; AKG, 2-oxoglutarate; AKGDH, 2-oxogluterate dehydrogenase; Cit, citrate; CS, citrate synthase; D-Glc, glucose; D-Glc-ext, external glucose; Fum, fumarate; FUM, fumarase; G6P, glucose 6-phosphate; G6PP, glucose-6-phosphate phosphatase; GLCex, Glucose Exchange; Glx, Glyoxylate; ICDHyr, isocitrate dehydrogenase; ICit, isocitrate; ICL, Isocitrate lyase; L-Mal, Malate; MALS, malate synthase; MDH, malate dehydrogenase; ME1, malic enzyme (NAD); OAA, oxaloacetate; PC, Pyruvate carboxylase; PCK1, phosphoenolpyruvate carboxykinase; PDH, pyruvate dehydrogenase; PEP, phosphoenolpyruvate; PYK, pyruvate kinase; Pyr, pyruvate; SUCC, succinyl; SUCCoA, succinyl-coenzyme A; SUCDi, succinate dehydrogenase; SUCOAS, succinyl-CoA synthetase.
Pey et al. Genome Biology 2011 12:R49 doi:10.1186/gb-2011-12-5-r49