Resolution:
## Figure 5.
Diagram of the method for comparing the extent and frequency of homozygous segments
with haplotypes underlying ext. From a consensus set of genotypes, homozygous segments were detected, ext_{AUC }peaks_{AUC }calculated and smooth spline interpolation performed, and peaks detected. Complementary
quantiles (Pr(X >Extent) = (1 - Pr(X ≤ Extent)) = (1 - Percentile/100)) were calculated from each ISLV's percentile values underlying
a particular peak. Values of Extent and Pr(X >Extent) that maximized the value of Extent × Pr(X >Extent) were extracted as parameters Extentand _{min }p, segments with length greater than _{max}Extentselected, and the maximum founder haplotype frequency (_{min }Freq) obtained across those segments. The expected haplotype frequency (_{hap-max}Freq) was calculated as the square-root of _{hap-exp}p.
_{max}Johnson |