Additional file 4.
FISH analysis of fusion genes. (a) Interphase FISH showing amplification of STARD3 and DOK5 (left), VAPB and CYTH1 (middle) and RPS6KB1 and SNF8 (right) in BT-474 cells but not in control cells. White arrows indicate fused genes. Coloring of the gene names coincides with labeling of the BAC clones used. (b) Interphase FISH showing amplified signals of BSG and NFIX (left) and NOTCH1 and NUP214 (right) in KPL-4. Normal copy number of both genes is present in control cells. (c) Interphase FISH analysis showing many copies of CYTH1 and EIF3H (left) and TATDN1 and GSDMB (right) in SK-BR-3. In contrast, only normal copy number of these genes is visible in control cells.
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Edgren et al. Genome Biology 2011 12:R6 doi:10.1186/gb-2011-12-1-r6