The first Irish genome and ways of improving sequence accuracy
1 Genomic Medicine Institute, Medical Research Center, Seoul National University, 28 Yongon-Dong, Jongno-Gu, Seoul 110-799, Korea
2 Department of Mathematics Education, Seoul National University, 599 Gwanak-ro, Gwanak-Gu, Seoul 151-742, Korea
3 Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, 28 Yongon-Dong, Jongno-Gu, Seoul 110-799, Korea
Genome Biology 2010, 11:132 doi:10.1186/gb-2010-11-9-132Published: 7 September 2010
Whole-genome sequencing of an Irish person reveals hundreds of thousands of novel genomic variants. Imputation using previous known information improves the accuracy of low-read-depth sequencing.