Additional file 2.

Flowchart of (a) methods and (b) analysis for the set of high-confidence domain gain events and for the set of medium-confidence domain gains. The numbers of gained domains we were left with after each filtering step are noted in (a). In some cases more domains were gained at the same time; hence, the number of gain events that we looked at for the high-confidence domain gains differs from the number of gained domains.

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Buljan et al. Genome Biology 2010 11:R74   doi:10.1186/gb-2010-11-7-r74