Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
1 London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
2 Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
3 Hines VA Hospital, Hines, IL 60141, USA
4 Institut Pasteur, rue du Dr Roux, 75724, Paris, France
Genome Biology 2009, 10:R102 doi:10.1186/gb-2009-10-9-r102Published: 25 September 2009
Additional data file 1:
CDS specific to PCR-ribotype 027 isolates.
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Additional data file 2:
Fourteen CDSs have been disrupted by an insertion in both 027 strains but are intact in 630, and, conversely, 12 CDSs are intact in both 027 strains but have been disrupted in 630.
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Additional data file 3:
R20291-specific gene primers used in this study.
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