Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules

Eran Hodis¹^,2^,7 , Jaime Prilusky³ , Eric Martz⁴ , Israel Silman²^,5 , John Moult⁶ and Joel L Sussman¹^,2

¹Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel

²The Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 76100, Israel

³Biological Services Unit, Weizmann Institute of Science, Rehovot 76100, Israel

⁴Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA

⁵Neurobiology Department, Weizmann Institute of Science, Rehovot 76100, Israel

⁶Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, MD 20850, USA

⁷Current Address: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel

author email corresponding author email

Genome Biology 2008, 9:R121doi:10.1186/gb-2008-9-8-r121


Published:	3 August 2008

Subject areas: Biochemistry and structural biology, Bioinformatics

Abstract

Many scientists lack the background to fully utilize the wealth of solved three-dimensional biomacromolecule structures. Thus, a resource is needed to present structure/function information in a user-friendly manner to a broad scientific audience. Proteopedia http://www.proteopedia.org webcite is an interactive, wiki web-resource whose pages have embedded three-dimensional structures surrounded by descriptive text containing hyperlinks that change the appearance (view, representations, colors, labels) of the adjacent three-dimensional structure to reflect the concept explained in the text.