Conservation of cycling genes. (a) Percentage of conserved cycling genes in the four species. (b) Enrichment of cell cycle related Gene Ontology GO terms between all cycling genes and the CCC3 set in budding yeast, fission yeast, and humans. (c) Yeast protein-protein interactions . We counted the number of interactions within a random set of 80 cycling yeast genes. In all, 1,000 sets were sampled. The histogram on the left plots the number of interactions observed for these sets. X represents internal interactions with the CCC3 set, which has significantly more internal interactions.
Lu et al. Genome Biology 2007 8:R146 doi:10.1186/gb-2007-8-7-r146