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How many genes in a genome?

Brian Oliver1* and Benoit Leblanc2

Author Affiliations

1 Laboratory of Cellular and Developmental Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, 50 South Dr. Bethesda, MD 20892-8028, USA

2 Département de Biologie, Faculté des Sciences, Université de Sherbrooke, 2500 boulevard Université, Sherbrooke, QC J1K 2R1, Canada

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Genome Biology 2003, 5:204  doi:10.1186/gb-2003-5-1-204

Published: 22 December 2003


Despite the current good level of annotation, the Drosophila genome still holds surprises. A recent study has added perhaps 2,000 genes to the predicted total, and raises a number of questions about how genome annotation data should be stored and presented.