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Articles selected by Faculty of 1000: Fat regulation in C. elegans; disease gene identification; comparision of mouse and human genomes; C. elegans early embryonic transcriptome; functional genomics in C. elegans
Genome Biology volume 4, Article number: 311 (2003)
Summary
A selection of evaluations from Faculty of 1000 covering several post-genomic studies in C. elegans, the use of 'integrative genomics' in disease gene identification and a comparison of mouse and human genomes.
Fat regulation in C. elegans
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. Nature 2003, 421:268-272.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Ashrafi
Disease gene identification
Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics. Mootha VK, Lepage P, Miller K, Bunkenborg J, Reich M, Hjerrild M, Delmonte T, Villeneuve A, Sladek R, Xu F, et al. Proc Natl Acad Sci U S A 2003, 100:605-610.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Mootha
Comparision of mouse and human genomes
Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Guigo R, Dermitzakis ET, Agarwal P, Ponting CP, Parra G, Reymond A, Abril JF, Keibler E, Lyle R, Ucla C, et al. Proc Natl Acad Sci U S A 2003, 100:1140-1145.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Guigo
C. elegans early embryonic transcriptome
Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. Baugh LR, Hill AA, Slonim DK, Brown EL, Hunter CP. Development 2003, 130:889-900.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Baugh
Functional genomics in C. elegans
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, et al. Nature 2003 421:231-237.
For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-311.asp#Kamath
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The Author(s). Articles selected by Faculty of 1000: Fat regulation in C. elegans; disease gene identification; comparision of mouse and human genomes; C. elegans early embryonic transcriptome; functional genomics in C. elegans . Genome Biol 4, 311 (2003). https://doi.org/10.1186/gb-2003-4-3-311
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DOI: https://doi.org/10.1186/gb-2003-4-3-311