Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Open Badges Web report

A 'handy' site for calcium-binding proteins

Julie Curran

Citation and License

Genome Biology 2000, 1:reports228  doi:10.1186/gb-2000-1-1-reports228

The electronic version of this article is the complete one and can be found online at:

Received:9 December 1999
Published:17 March 2000

© 2000 BioMed Central Ltd


This is a great site for calcium-binding protein enthusiasts. Each protein has its own page which contains general information and a reference list with a search option. Sequence information from each protein includes descriptions of the loop structures, and the picture gallery has great images of protein conformations and substrate binding. Three-dimensional structural information on each protein family is given through links to protein databank files that can be downloaded by FTP, and there are a couple of tools in the site that allow you to compare structural aspects of different proteins (one of these is restricted to internal access).


An excellent design makes navigation through this site very easy. Each page has the option of returning to the home page or to the first page of each of the four subsections.

Reporter's comments


No indication of when the site was last updated could be found.

Best feature

The picture gallery gives good images of a number of proteins showing conserved residues and conformations of proteins when substrate is bound.

Worst feature

Some information is missing from each individual protein page, but it is not clear whether this information is not available or simply has not been entered

Wish list

It might benefit some researchers to be able to use the second tool listed in the analytical tools page, which is currently of restricted access.

Table of links

Assumptions made about all sites unless otherwise specified:
The site is free, in English and no registration is required. It is relatively quick to download, can be navigated by an 'intermediate' user, and no problems with connection were found. The site does not stipulate that any particular browser be used and no special software/plug-ins are required to view the site. There are relatively few gratuitous images and each page has its own URL, allowing it to be bookmarked.