Genome Biology aims to provide the best possible service to authors and readers of primary research articles. The refereed research section publishes peer-reviewed research in all areas of molecular, cellular, organismal and population biology that are informed by genomics. All research articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how refereed research is published in Genome Biology and for instructions for authors, see 'about refereed research'.

Research    

(5 August 2008)

Human cognitive evolution involved genes implicated in energy metabolism and energy-expensive brain functions that are also altered in schizophrenia, suggesting that human brains may have reached their metabolic limit, with schizophrenia as a costly by-product.

Research    

(27 August 2008)

The testis transcriptome of mouse strains containing homozygous segments of Mus spretus origin in a Mus musculus background was analyzed.

Software    

(15 August 2008)

MotifCluster finds related motifs in a set of sequences and clusters the sequences into families using the motifs they contain.

Research    

(18 August 2008)

Multiparallel QTL analysis of 15 Arabidopsis primary carbohydrate metabolism enzymes reveals that traits affecting primary metabolism are often correlated.

Research    

(26 August 2008)

Analysis of duplicate genes and predicted microRNA targets in human and mouse shows that microRNAs are important in how the regulatory patterns of mammalian paralogs have evolved.

Software    

(3 August 2008)

Proteopedia is an interactive wiki-style web resource that presents 3D structural and functional information in a user-friendly manner and allows real-time community annotation.

Research    

(21 August 2008)

The first genomic and chemical characterization of fruit fly neuropeptides outside Drosophila melanogaster provides insights into the evolution of the neuropeptidome in this genus.

Research    

(12 August 2008)

Analysis of six Drosophila simulans genotypes revealed that genes with greater variation in gene expression between genotypes also have higher levels of sequence polymorphism in many gene features.