Biology for the post-genomic era

Fully Open Access. Genome Biology covers all areas of biology and biomedicine studied from a genomic and post-genomic perspective. Content includes research, new methods and software tools, and reviews, opinions and commentaries. Areas covered include, but are not limited to: sequence analysis; bioinformatics; insights into molecular, cellular and organismal biology; functional genomics; epigenomics; population genomics; proteomics; comparative biology and evolution; systems and network biology; genomics of disease; and clinical genomics. All content is open access immediately on publication.


  • Louisa Flintoft PhD, Genome Biology


There has been an error retrieving the data. Please try again.
  • THS-Seq

    A transposome hypersensitive sites sequencing assay enables highly sensitive characterization of chromatin accessibility

    Genome Biology 2016, 17:20
  • lncRNA analysis across mammals

    An analysis of lncRNAs across mammals indicates these RNAs are a mixture of multiple functional classes with distinct biological roles

    Genome Biology 2016, 17:19
  • Epigenetics and cell differentiation

    A new study shows how a single cytokine regulates hematopoietic lineage choice by activating a pathway, which causes dendritic-cell-specific DNA demethylation

    Genome Biology 2016, 17:18
  • Proteome diversification by Alu

    A new study examines the input of Alu transposons into human genes

    Genome Biology 2016, 17:17
  • Variability of lncRNAs

    Long non-coding RNAs display higher natural expression variability than protein-coding genes in healthy humans

    Genome Biology 2016, 17:14
  • Alu exons and human proteins

    This article suggests that Alu elements have contributed to the acquisition of novel protein sequences during primate and human evolution

    Genome Biology 2016, 17:15
  • RNA-seq analysis methods

    A comprehensive review of RNA-seq data analysis from experimental design, through read mapping and quantification, to visualization and functional analysis

    Genome Biology 2016, 17:13
  • Cancer super-enhancer methylation

    Whole genome bisulfite sequencing in human cancers shows specific aberrant DNA methylation patterns at super-enhancers

    Genome Biology 2016, 17:11
  • Finding mutations in cfDNA

    Sequencing of cfDNA of prostate cancer patients identifies a number of androgen receptor mutations with clinical relevance

    Genome Biology 2016, 17:10
  • Genetics of mate choice

    This study examines the drivers of mate choice, and finds that genes contributing to height affect individual preferences for mate’s height

    Genome Biology 2016, 16:269
  • Predicting pathogenic mutations

    This article describes an approach to indicate intolerant regions in functionally distinct portions of genes: exons and protein domains

    Genome Biology 2016, 17:9
Genome Editing: read the special issue
Single-cell omics: call for papers
Wheat genomics: featured research
3D Organization of the Nucleus
Avian Genomes collection
Submit a manuscript Sign up for article alerts Contact us

Email updates

Receive periodic news and updates relating to this journal straight to your inbox.

Indexed by

  • CAS
  • PubMed
  • Science Citation Index
  • Scopus

View all

ISSN: 1474-760X