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  • Microbiome profiling from biopsies

    Doron Betel and colleagues describe methodology for the identification of pathogens from low bacterial abundance human WGS datasets

    Genome Biology 2015, 16:265
  • Down syndrome methylation

    Novel biological mechanisms are implicated in the development of Down syndrome by studying methylation patterns in humans and mice

    Genome Biology 2015, 16:263
  • S. aureus alternative Cas9

    A characterization of an alternative, Staphylococcus aureus-derived Cas9 nuclease and the design of all-in-one vector

    Genome Biology 2015, 16:257
  • p16 DNA methylation drives metastasis

    Engineered zinc finger methyltransferases provide insights into the role of p16 methylation in cancer metastasis

    Genome Biology 2015, 16:252
  • Cas9 PAM characterization

    A new in vitro method for simultaneous examination of guide RNA and PAM requirements for CRISPR-based experiments

    Genome Biology 2015, 16:253
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