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Different ways to make neurons: parallel evolution in the SoxB family

Nathalie Neriec12 and Claude Desplan12*

Author Affiliations

1 Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, NY 10003-6688, USA

2 Center for Genomics & Systems Biology, New York University Abu Dhabi Institute, Abu Dhabi, UAE

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Genome Biology 2014, 15:116  doi:10.1186/gb4177

Published: 30 May 2014


Combining genome-wide analyses of binding sites and expression profiles generates a model for the functional evolution of two SOXB paralogous proteins in neurogenesis.

Neuronal development; SoxB; Functional conservation; Drosophila