Additional file 1.

Methylation validation using Sanger sequencing. For validation of the methylation data from BeadChip, 17 genes were chosen, including unmethylated sites (n = 1), fully methylated sites (n = 2), and genes with tDMRs (n = 14) representing 36 CpG sites altogether. The x-axis shows DNA methylation beta-values obtained from BeadChip, and the y-axis shows beta values from Sanger sequencing.

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Lokk et al. Genome Biology 2014 15:r54   doi:10.1186/gb-2014-15-4-r54