DNA methylation and gene expression correlation in CGI-promoter regions and the gene body. (A) Correlation analysis of CGI-promoter methylation and gene expression show that genes with low expression have high methylation. (B) Gene body methylation and gene expression are not correlated. (A, B) The x-axis shows DNA methylation beta values, and the y-axis shows gene expression values. The different tissues studied are represented by the following symbols: aortas (•), coronary artery (●), bladder (), bone (), bone marrows (), lymph node (), medulla oblongata (+), and tonsils (×).
Lokk et al. Genome Biology 2014 15:r54 doi:10.1186/gb-2014-15-4-r54