Figure 4.

Comparison of the distribution of fitness effect of mutations occurring within lncRNAs in D. melanogaster and human. For comparison the distributions were also computed for the 5′ and 3′ UTRs of protein-coding genes in D. melanogaster and human, as well as for 0-fold degenerate sites at genes annotated in the OMIM database or with lethal mutant phetnotype in D. melanogaster, and for 0-fold degenerate sites from the remaining non-annotated protein-coding genes. The distributions were computed using DFE alpha [101], the values represent the average over 200 boostraps for each locus in each category.

Haerty and Ponting Genome Biology 2013 14:R49   doi:10.1186/gb-2013-14-5-r49
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