Median sequence conservation (phastCons) score across protein coding (blue) and lncRNA (red) exons and introns in D . melanogaster (A) and in human (B). Non-overlapping windows each comprising 10% of the sequences were used. The shaded areas represent the 95% confidence intervals over the median. The grey lines represent the median scores computed using 1,000 resampling of intergenic sequences matching the lncRNA size distribution.
Haerty and Ponting Genome Biology 2013 14:R49 doi:10.1186/gb-2013-14-5-r49