Additional file 12.

Figure S3 - schematic diagrams of fusion event RECK-ALX3. (a) Alignment of supporting reads against the predicted junction sequence. The upstream part of the junction sequence is in green, and the downstream part is in red. Span-reads are displayed above the predicted junction sequence with the colored dotted line linking paired-end reads. Junc-reads are shown below the junction sequence. (b,c) Expression analysis of the exons in RECK and ALX3 by RNA-Seq read coverage. Transcripts of RECK and ALX3 are shown below the coordinates. The junction site is shown as a red round dot and a green arrow indicates the transcript orientation in the genome sequence. The region covered by the red line is the region mapped by supporting reads. In this case, we found that the expression levels of RECK and ALX3 exons at bilateral sides of junction sites are significantly different. The exons involved in the fusion transcript are expressed more highly than other ones.

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Jia et al. Genome Biology 2013 14:R12   doi:10.1186/gb-2013-14-2-r12