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The spliceosomal catalytic core arose in the RNA world… or did it?

W Ford Doolittle

Author Affiliations

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada

Genome Biology 2013, 14:141  doi:10.1186/gb4145

Published: 13 December 2013


A new study adds to the evidence for a common evolutionary origin of the spliceosome and group II introns, but RNA-world questions remain.