Influence of CCR-Δ32 on different stages of HIV AIDS. (a) HIV transmission/acquisition. The frequency (percentage) of CCR-Δ32 genotypes among HIV infected versus HIV uninfected people in cumulative AIDS cohorts (total n = 17,214 study participants) [12-14,79,101]. (b) AIDS progression in HIV-infected people. Kaplan-Meier survival curves comparing the rate of AIDS onset in CCR+/+ versus CCR5+/Δ32 [12,79,101]. (c) Progression to AIDS post HAART therapy. Kaplan-Meier survival curves comparing the rate of AIDS onset in CCR+/+ versus CCR5+/Δ32 .
O'Brien and Hendrickson Genome Biology 2013 14:201 doi:10.1186/gb-2013-14-1-201