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Evolutionary insights into genome-wide nucleosome positioning

Vijender Singh and Tom Owen-Hughes*

Author affiliations

Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK

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Citation and License

Genome Biology 2012, 13:170  doi:10.1186/gb-2012-13-9-170

Published: 27 September 2012


A new study takes an evolutionary approach to investigate to what extent nucleosome positioning is determined by underlying sequence or by trans-acting factors.

Evolution; genome-wide organization; nucleosome positioning; poly(dA:dT) sequences; yeast