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The multiplicity of divergence mechanisms in a single evolving population

Ram P Maharjan1, Thomas Ferenci1, Peter R Reeves1, Yang Li23, Bin Liu23 and Lei Wang23*

Author Affiliations

1 School of Molecular and Microbial Biosciences, University of Sydney, NSW 2006, Australia

2 TEDA School of Biological Sciences and Biotechnology, Nankai University, 23 Hongda Street, Tianjin 300457, PR China

3 Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, 23 Hongda Street, Tianjin 300457, PR China

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Genome Biology 2012, 13:R41  doi:10.1186/gb-2012-13-6-r41

Published: 8 June 2012

Additional files

Additional file 1:

Supplementary Tables S1 to S4 and Figures S1 and S2. Table 1: phenotypic characteristics of 320 E. coli isolates evolving under glucose-limited limited. Table 2: groupings of phenotypic properties found in eight glucose-limited populations of E. coli. Table 3: clones chosen for full genome resequencing. Table 4: genomic changes detected in the 44 non-mutator evolved clones. Figure 1: maintenance of phenotypic diversity in an E. coli population evolving in a glucose-limited chemostat. Figure 2: relative level of RpoS protein in glucose-limited chemostats.

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Additional file 2:

SNPs of 48 strains compared with BW2952. Sheet 1: SNPs of slow-growth isolates. Sheet 2: SNPs of fast-growth isolates. Sheet 3: the SNPs of isolates with mutY mutator.

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