Mixture signal in the mtDNA dataset. The title of each plot shows the major component, minor component, average coverage, and mixture proportion. Expected minor alleles and observed minor alleles are shown in different colors. A, observed minor alleles likely due to mixture, verified by our method; B, observed minor alleles likely due to mixture, not verified by our method; C, missed minor alleles expected due to mixture; D, observed minor alleles not due to mixture.
Li and Stoneking Genome Biology 2012 13:R34 doi:10.1186/gb-2012-13-5-r34