Additional file 2.
Figure S2. Original log 2 transformed raw CodeLink microarray data shown in an MA-plot. Upper panel: the x-axis shows the average of the average gene expression of BF and FF infants for each probe. The y-axis shows the difference between the two averages. The color bar shows the count density of the plotted data. BF samples exhibited a systematically higher gene expression level relative to FF samples. Lower panel: loess normalization of the original log 2 transformed raw CodeLink microarray data. This normalization procedure corrected for the systematic increase in BF gene expression relative to FF gene expression seen in the upper panel. The data were adjusted by the loess fit (blue line) shown in the upper panel.
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Schwartz et al. Genome Biology 2012 13:r32 doi:10.1186/gb-2012-13-4-r32