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All Your Base: a fast and accurate probabilistic approach to base calling

Tim Massingham* and Nick Goldman

Author Affiliations

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1RQ, UK

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Genome Biology 2012, 13:R13  doi:10.1186/gb-2012-13-2-r13

Published: 29 February 2012

Additional files

Additional file 1:

Fitting a block tridiagonal information matrix by ML. Additional data file 1 is a document describing how to find the maximum likelihood estimate of the inverse covariance matrix when several of its components are conditionally independent. webcite.

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