Cell cycle and cell size effects of microRNAs let-7, miR-125, and miR-29. (A) Cell cycle progression of serum-restimulated quiescent cells with simultaneous transfection of miR-29, let-7, miR-125, a combination of let-7 and miR-125, or a negative control (NC) non-targeting miRNA. The fraction of cells in different cell cycle phases is plotted with error bars of the residual sums of squares from two timecourses measured in triplicate. (B) Cell cycle phase distribution of asynchronously proliferating fibroblasts 48 h after transfection with miR-29. (C) Cell numbers 48 h after miR-29 transfection. (D) Cell sizes 48 h after miR-29 transfection.
Suh et al. Genome Biology 2012 13:R121 doi:10.1186/gb-2012-13-12-r121