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FOCAL: an experimental design tool for systematizing metabolic discoveries and model development

Christopher J Tervo and Jennifer L Reed*

Author Affiliations

Department of Chemical and Biological Engineering, University of Wisconsin - Madison, WI 53706, USA

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Genome Biology 2012, 13:R116  doi:10.1186/gb-2012-13-12-r116

Published: 13 December 2012

Additional files

Additional file 1:

List of the maximum uptake rates and media components for the three genome-scale models.

Format: XLS Size: 103KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Supplementary material, including additional algorithm details, supplementary tables, and supplementary figures.

Format: PDF Size: 1.8MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

An implementation of FOCAL for the example network shown in Figure 2. This file can be run by GAMS (GAMS Development Corporation, Washington, DC), which can be freely downloaded at [38].

Format: ZIP Size: 22KB Download file

Open Data