Crystal structure of the human ADAR2 deaminase domain shown from the top (a) and side (b). The catalytic core is formed between H394 (red), E396 (blue), C451 (orange) and C516 (gray). The core also includes a water molecule, zinc ion and IP6 molecule (not shown).
Savva et al. Genome Biology 2012 13:252 doi:10.1186/gb-2012-13-12-252