Phylogenetic tree of dnmt proteins. Multiple sequence alignment was performed by ClusterW, then ClusterW with the neighbor-joining method based on JTT+ G (Jones-Taylor-Thornton and Gamma Distribution) model was applied to reconstruct the phylogenetic tree. The species with best hits to T. spiralis dnmts were used as representatives that span the phylum and were analyzed in this study.
Gao et al. Genome Biology 2012 13:R100 doi:10.1186/gb-2012-13-10-r100