Additional file 2.

Effect of aligner on peak detection. Realigning the MeRIP-seq HEK293T data using three different aligners, with MeRIPPeR as the peak caller, shows that the peak distribution is dependent on the aligner chosen. Using TopHat 2 increases the number of 5' UTR peaks detected.

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Saletore et al. Genome Biology 2012 13:175   doi:10.1186/gb-2012-13-10-175