Genotype sensitivity. (a) Genotype sensitivity of six replicates at 30× sequencing depth. (b) Genotype sensitivity as a function of sequencing depth. For the analyses, subsets of reads from two combined replicate datasets for each platform were randomly extracted at different average depths. NA, NS and AS represent NimbleGen Sequence Capture Arrays, NimbleGen SeqCap EZ and Agilent SureSelect, respectively, while r1 and r2 are two replicate experiments for each platform.
Asan et al. Genome Biology 2011 12:R95 doi:10.1186/gb-2011-12-9-r95