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This article is part of a special issue on exome sequencing.

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Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice

Jennifer M Hilton, Morag A Lewis, M'hamed Grati, Neil Ingham, Selina Pearson, Roman A Laskowski, David J Adams and Karen P Steel*

Genome Biology 2011, 12:R90  doi:10.1186/gb-2011-12-9-r90