Table 4

In silico analysis of all induced or spontaneous alleles (4,984) with phenotypes reported in the Mouse Genomes Database [1]


Number of alleles

Unknown or uncharacterized


Introns, UTRs, regulatory regions (including instances where the lesion is not known but coding sequence has been sequenced), cryptic splice sites, inversions


Exons (single nucleotide substitutions, deletions, insertions)


Conserved splice acceptor or donor


This analysis shows that the vast majority of induced or spontaneous alleles that have been characterized at the molecular level (1,879) are mutations in coding sequence or conserved splice acceptor/splice donor sites.

Fairfield et al. Genome Biology 2011 12:R86   doi:10.1186/gb-2011-12-9-r86

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