This article is part of a special issue on exome sequencing.

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Reducing the exome search space for Mendelian diseases using genetic linkage analysis of exome genotypes

Katherine R Smith*, Catherine J Bromhead, Michael S Hildebrand, A Eliot Shearer, Paul J Lockhart, Hossein Najmabadi, Richard J Leventer, George McGillivray, David J Amor, Richard J Smith and Melanie Bahlo

Genome Biology 2011, 12:R85  doi:10.1186/gb-2011-12-9-r85

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