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Hybrid selection for sequencing pathogen genomes from clinical samples

Alexandre Melnikov1, Kevin Galinsky1, Peter Rogov1, Timothy Fennell1, Daria Van Tyne2, Carsten Russ1, Rachel Daniels1, Kayla G Barnes2, James Bochicchio1, Daouda Ndiaye3, Papa D Sene3, Dyann F Wirth2, Chad Nusbaum1, Sarah K Volkman2, Bruce W Birren1, Andreas Gnirke1 and Daniel E Neafsey1*

Author Affiliations

1 Genome Sequencing and Analysis Program, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA

2 Department of Immunology and Infectious Disease, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA

3 Faculty of Medicine and Pharmacy, Cheikh Anta Diop University, BP 7325, Dakar, Senegal

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Genome Biology 2011, 12:R73  doi:10.1186/gb-2011-12-8-r73

Published: 11 August 2011

Additional files

Additional file 1:

Sequencing coverage comparison for 10-kb genomic windows.

Format: PDF Size: 507KB Download file

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Additional file 2:

Genomic locations of Agilent synthetic baits.

Format: XLS Size: 2.3MB Download file

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Additional file 3:

P. falciparum qPCR primers and locations (3D7 v.5.0 assembly).

Format: DOC Size: 33KB Download file

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Open Data