Figure 1.

Read distributions around two fusions: BCAS4-BCAS3 and TOB1-SYNRG. (a) Sixty reads aligned by TopHat-Fusion that identify a fusion product formed by the BCAS4 gene on chromosome 20 and the BCAS3 gene on chromosome 17. The data contained more reads than shown; they are collapsed to illustrate how well they are distributed. The inset figures show the coverage depth in 600-bp windows around each fusion. (b) TOB1 (ENSG00000141232)-SYNRG is a novel fusion gene found by TopHat-Fusion, shown here with 70 reads mapping across the fusion point. Note that some of the reads in green span an intron (indicated by thin horizontal lines extending to the right), a feature that can be detected by TopHat's spliced alignment procedure.

Kim and Salzberg Genome Biology 2011 12:R72   doi:10.1186/gb-2011-12-8-r72
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