Protein categories enriched in codon sites under positive selection tend to have higher average levels of intrinsically disordered regions compared to categories enriched in sites under negative selection. (a) MIPS FunCat categories are plotted in a rank according to their IDR content (small open circles). Categories from Figure 5a that are enriched in codon sites under positive (filled squares) or negative (open triangles) selection are plotted with a larger symbol. (b) MIPS ProteinCat classes, including those enriched in codon sites under selection (Figure 5b), are plotted as in (a).
Nilsson et al. Genome Biology 2011 12:R65 doi:10.1186/gb-2011-12-7-r65