Additional file 5.

MMSEQ vs. RSEM scatterplots. Normalized simulated expression vs. log ratio between simulated and estimated normalized expression for RSEM (left) and MMSEQ GS (right) (note the difference in the scales of the y-axes). The RSEM estimates tend to underestimate some low-to-medium expression values and set them very close to zero, which translates to large negative log ratios. This also applies to MMSEQ EM estimates. The posterior means estimated using MMSEQ Gibbs sampling are less biased except for a slight upwards bias for very lowly expressed transcripts.

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Turro et al. Genome Biology 2011 12:R13   doi:10.1186/gb-2011-12-2-r13