Heat shock factor binding motif and preferred binding sites in Alu repeats of heat shock responsive transcripts. The frequency of three preferred binding sites of HSFs mapped on to Alu repeats, in both sense and antisense orientations, of heat shock responsive transcripts is shown. The HSF site at position 221 is common between both sense and antisense Alus. Sites at positions 175 and 91 are unique to sense and antisense Alus, respectively. The inset shows the consensus motif for HSF sites across all Alu subfamilies.
Pandey et al. Genome Biology 2011 12:R117 doi:10.1186/gb-2011-12-11-r117