Additional file 5.

DNA shearing optimization. Profiles of sheared genomic DNA from unoptimized (blue) and optimized (red) conditions are shown. The size distribution from optimized conditions has a larger fraction of product DNA in the desired size range of 120 to 150 bases. The sharp peaks at approximately 20 and approximately 1,500 bases represent size standards.

Format: PDF Size: 402KB Download file

This file can be viewed with: Adobe Acrobat Reader

Fisher et al. Genome Biology 2011 12:R1   doi:10.1186/gb-2011-12-1-r1