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Screening the human exome: a comparison of whole genome and whole transcriptome sequencing

Elizabeth T Cirulli1, Abanish Singh1, Kevin V Shianna1, Dongliang Ge1, Jason P Smith1, Jessica M Maia1, Erin L Heinzen1, James J Goedert2, David B Goldstein1* and the Center for HIV/AIDS Vaccine Immunology (CHAVI)

Author Affiliations

1 Center for Human Genome Variation, Duke University School of Medicine, Box 91009, Durham, NC 27708, USA

2 Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, US National Cancer Institutes of Health, 6120 Executive Boulevard, Rockville, MD 20852, USA

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Genome Biology 2010, 11:R57  doi:10.1186/gb-2010-11-5-r57

Published: 28 May 2010

Additional files

Additional file 1:

Supplemental figures S1 to S4. Showing the specificity at different read depth levels and the overlap with dbSNP entries at different coverage levels and different expression levels.

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