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Genome-wide functional analysis of human 5' untranslated region introns

Can Cenik1, Adnan Derti1, Joseph C Mellor1, Gabriel F Berriz1 and Frederick P Roth12*

Author Affiliations

1 Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, 250 Longwood Avenue, SGMB-322, Boston, MA 02115, USA

2 Center for Cancer Systems Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA

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Genome Biology 2010, 11:R29  doi:10.1186/gb-2010-11-3-r29

Published: 11 March 2010

Additional files

Additional file 1:

Complete list of RefSeq mRNA IDs that have 5'UTR introns. This file contains the genomic coordinates and RefSeq IDs for all transcripts with 5'UTR introns. '+'and '-' represent the forward and reverse strands, respectively.

Format: TXT Size: 800KB Download file

Open Data

Additional file 2:

Complete list of 5'UTR intron lengths for the human non-receptor tyrosine kinases and their orthologs in mouse and rat genomes. This file contains the RefSeq IDs and gene symbols for all human NRTKs and their mouse and rat orthologs. For all transcripts, 5'UTR intron lengths are given.

Format: TXT Size: 2KB Download file

Open Data

Additional file 3:

Overrepresented GO attributes for genes with 5'-proximal coding introns. This file contains the table of overrepresented GO attributes for genes with 5'-proximal coding introns. The methods and legend are the same as in Table 1.

Format: PDF Size: 40KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data