Effect of nucleosome alignment on CTCF correlated histone modifications. (a,c) Plots of the average tag counts at the unaligned and aligned CTCF sites for (a) H2A.Z and (c) H3K4me3. (b,d) Sequence tag data for H2A.Z at CTCF sites was clustered into two groups by k-means clustering after centering each region by average tag count . The average profiles for the two groups for (b) H2A.Z and (d) H3K4me3 were plotted.
Lai and Buck Genome Biology 2010 11:R126 doi:10.1186/gb-2010-11-12-r126